pentobarbital will decrease the level or impact of fosamprenavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will lower the level or impact of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will lessen the level or outcome of naloxegol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Usage of naloxegol with solid CYP3A4 inducers will not be recommended
fentanyl intranasal and pentobarbital each raise sedation. Stay clear of or Use Alternate Drug. Limit use to sufferers for whom different treatment choices are insufficient
pentobarbital will reduce the extent or impact of isradipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unidentified.
pentobarbital will lower the extent or effect of irinotecan liposomal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital and daridorexant equally enhance sedation. Modify Therapy/Watch Carefully. Coadministration increases hazard of CNS melancholy, which can result in additive impairment of psychomotor efficiency and bring about daytime impairment.
pentobarbital will enhance the amount or result of clopidogrel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Observe Closely (two)pentobarbital will decrease the extent or result of buprenorphine, extensive-performing injection by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Closely. Patients who transfer to buprenorphine extensive-acting injection from transmucosal buprenorphine coadministered with CYP3A4 inducers should be monitored to be certain buprenorphine plasma concentrations are suitable.
pentobarbital will reduce the level or impact of etoposide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Monitor Closely (one)pentobarbital will lessen the level or result of hydrocodone get more info by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Warning when discontinuing CYP3A4 inducers that are coadministered with hydrocodone; plasma concentrations of hydrocodone might improve and can lead to possibly lethal respiratory depressionSerious - Use Choice (one)hydrocodone, pentobarbital.
Monitor Closely (1)pentobarbital will lower the extent or influence of glecaprevir/pibrentasvir by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Contraindicated. CYP3A4 is to blame for the formation and elimination of cariprazine's Energetic metabolites. The impact of CYP3A4 inducers on cariprazine publicity hasn't been evaluated plus the net influence is unclear.
fentanyl iontophoretic transdermal program and pentobarbital equally enhance sedation. Keep away from or Use Alternate Drug. Limit use to clients for whom alternate cure selections are inadequate